JPH0586390B2 - - Google Patents

Info

Publication number
JPH0586390B2
JPH0586390B2 JP59200717A JP20071784A JPH0586390B2 JP H0586390 B2 JPH0586390 B2 JP H0586390B2 JP 59200717 A JP59200717 A JP 59200717A JP 20071784 A JP20071784 A JP 20071784A JP H0586390 B2 JPH0586390 B2 JP H0586390B2
Authority
JP
Japan
Prior art keywords
formula
atoms
carboline
lower alkyl
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP59200717A
Other languages
English (en)
Japanese (ja)
Other versions
JPS60100577A (ja
Inventor
Fuuto Andoreasu
Shumiihien Rarufu
Raatsu Deiitaa
Zaideruman Deiitaa
Chiko Buresutoruupu Kurausu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of JPS60100577A publication Critical patent/JPS60100577A/ja
Publication of JPH0586390B2 publication Critical patent/JPH0586390B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Treating Waste Gases (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Carbon And Carbon Compounds (AREA)
JP59200717A 1983-09-27 1984-09-27 置換β−カルボリン誘導体、その製法及び該誘導体を含有する向精神薬 Granted JPS60100577A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3335323.9 1983-09-27
DE3335323A DE3335323A1 (de) 1983-09-27 1983-09-27 Substituierte ss-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
JPS60100577A JPS60100577A (ja) 1985-06-04
JPH0586390B2 true JPH0586390B2 (en]) 1993-12-10

Family

ID=6210425

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59200717A Granted JPS60100577A (ja) 1983-09-27 1984-09-27 置換β−カルボリン誘導体、その製法及び該誘導体を含有する向精神薬

Country Status (18)

Country Link
US (1) US4623649A (en])
EP (1) EP0137390B1 (en])
JP (1) JPS60100577A (en])
AT (1) ATE55604T1 (en])
AU (1) AU578043B2 (en])
CA (1) CA1263394A (en])
DD (1) DD223714A5 (en])
DE (2) DE3335323A1 (en])
DK (1) DK170256B1 (en])
ES (1) ES8505368A1 (en])
FI (1) FI843777L (en])
GR (1) GR80482B (en])
HU (1) HU200457B (en])
IE (1) IE57670B1 (en])
IL (1) IL73071A (en])
NO (1) NO160998C (en])
PT (1) PT79264B (en])
ZA (1) ZA847619B (en])

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK240184D0 (da) * 1984-05-15 1984-05-15 Ferrosan As Beta-carboline-3-carboxylic acid derivatives and method of preparing the same
DK240084D0 (da) * 1984-05-15 1984-05-15 Ferrosan As New beta-carboline-3-oxadiazolyl derivatives
DE3535927A1 (de) * 1985-10-04 1987-04-09 Schering Ag 3-vinyl- und 3-ethinyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE3540653A1 (de) * 1985-11-13 1987-05-14 Schering Ag Neue 3-oxadiazol- und 3-carbonsaeure-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE3545776A1 (de) * 1985-12-20 1987-06-25 Schering Ag 5-aminoalkyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
US4952584A (en) * 1986-01-11 1990-08-28 Beecham Group P.L.C. 9H-pyrido[2,B-8]indole-3-carboxylic acid ester compounds having useful pharmaceutical activity
DE3609699A1 (de) * 1986-03-20 1987-09-24 Schering Ag 5- oder 6-substituierte-(beta)-carbolin-3-carbonsaeureester
DE3608089A1 (de) * 1986-03-08 1987-09-10 Schering Ag Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE4130933A1 (de) * 1991-09-13 1993-03-18 Schering Ag Neue (beta)-carbolinderivate, deren herstellung und verwendung in arzneimitteln
US5585490A (en) * 1991-10-08 1996-12-17 Neurogen Corporation Certain cycloalkyl and azacycloalkyl pyrrolopyrimidines; a new class of GABA brain receptor ligands
US5367077A (en) * 1992-04-08 1994-11-22 Neurogen Corporation Certain cycloalkyl and azacycloalkyl pyrrolopyridines; a new class of gaba rain receptor ligands
AU4117493A (en) * 1992-04-08 1994-11-21 Neurogen Corporation Certain aryl fused pyrrolopyrimidines; a new class of gaba brain receptor ligands
US5286860A (en) * 1992-11-12 1994-02-15 Neurogen Corporation Certain aryl substituted pyrrolopyrazines; a new class of GABA brain receptor ligands
US5750702A (en) * 1993-10-27 1998-05-12 Neurogen Corporation Certain pyrrolo pyridine-3-carboxamides; a new class of GABA brain receptor ligands
US5484944A (en) * 1993-10-27 1996-01-16 Neurogen Corporation Certain fused pyrrolecarboxanilides and their use as GABA brain receptor ligands
US5804686A (en) * 1996-01-19 1998-09-08 Neurogen Corporation fused pyrrolecarboxamides; a new class of GABA brain receptor ligands
US6211365B1 (en) 1996-01-19 2001-04-03 Neurogen Corporation Fused pyrrolecarboxamides; a new class of GABA brain receptor ligands
EP0888300A1 (en) 1996-03-22 1999-01-07 Neurogen Corporation Certain fused pyrrolecarboxamides as gaba brain receptor ligands
US5723462A (en) * 1996-04-26 1998-03-03 Neurogen Corporation Certain fused pyrrolecarboxamides a new class of GABA brain receptor ligands
PL354513A1 (en) 1999-08-31 2004-01-26 Neurogen Corporation Fused pyrrolecarboxamides: gaba brain receptor ligands
US20050014939A1 (en) * 1999-08-31 2005-01-20 Neurogen Corporation Fused pyrrolecarboxamides: GABA brain receptor ligands
US20030045541A1 (en) * 2001-07-23 2003-03-06 Christopher Bruckner GABA-Receptor modulators with NMDA-Antagonistic activity

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3058909A (en) 1957-07-23 1962-10-16 Atlantic Refining Co Method and composition for formation fracturing
US3163219A (en) 1961-06-22 1964-12-29 Atlantic Refining Co Borate-gum gel breakers
US3215634A (en) 1962-10-16 1965-11-02 Jersey Prod Res Co Method for stabilizing viscous liquids
GB1084257A (en]) * 1963-11-06
US3741894A (en) 1967-06-15 1973-06-26 Exxon Production Research Co Chemically modified organic polymers
US3696035A (en) 1970-11-04 1972-10-03 Dow Chemical Co Well treatments with thickened aqueous alcohol mixtures
US3727688A (en) 1972-02-09 1973-04-17 Phillips Petroleum Co Hydraulic fracturing method
US3768566A (en) 1972-04-18 1973-10-30 Halliburton Co Methods for fracturing high temperature well formations
US3848673A (en) 1973-02-26 1974-11-19 Phillips Petroleum Co Recovery of hydrocarbons
US4033415A (en) 1973-03-30 1977-07-05 Halliburton Company Methods for fracturing well formations
DE2415154C2 (de) 1974-03-29 1985-05-23 Henkel KGaA, 4000 Düsseldorf Verfahren zur Herstellung von Cellulosemischethern, die neben Alkylgruppen, Hydroxyalkylgruppen oder Carboxyalkylgruppen noch 2,3-Dihydroxypropylgruppen enthalten
DE2415155C2 (de) 1974-03-29 1985-05-23 Henkel KGaA, 4000 Düsseldorf Verfahren zur Herstellung von 2,3-Dihydroxypropylcellulose
US3888312A (en) 1974-04-29 1975-06-10 Halliburton Co Method and compositions for fracturing well formations
US3978928A (en) 1975-04-14 1976-09-07 Phillips Petroleum Company Process for the production of fluids from subterranean formations
US4144179A (en) 1975-07-21 1979-03-13 Halliburton Company Composition for treating low temperature subterranean well formations
US4096326A (en) 1976-10-13 1978-06-20 Hercules Incorporated Dihydroxypropyl cellulose
US4323123A (en) 1978-07-17 1982-04-06 Phillips Petroleum Company Gelled compositions and well treating
NZ194747A (en) * 1979-08-29 1988-11-29 Schering Ag 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives
DE3023567A1 (de) * 1980-06-20 1982-01-21 Schering Ag, 1000 Berlin Und 4619 Bergkamen Substituierte (beta) -carbolin-3-carbonsaeurederivate
JPS574987A (en) * 1980-06-09 1982-01-11 Sankyo Co Ltd Pyridoindolecarboxylic acid derivative and its preparation
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
DE3136857A1 (de) * 1981-09-14 1983-03-31 Schering Ag, 1000 Berlin Und 4619 Bergkamen Substituierte (beta)-carbolin-3-carbonsaeurealkylester, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3048318A1 (de) * 1980-12-17 1982-07-22 Schering Ag, 1000 Berlin Und 4619 Bergkamen 4-alkoxyalkyl substituierte (beta)-carbolin-3-carbonsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
EP0089100B1 (en) * 1982-02-09 1989-05-31 Imperial Chemical Industries Plc Azolyl derivatives as fungicides
DE3240511A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von ss-carbolinderivaten
DE3240513A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Indolderivate, verfahren zu ihrer herstellung und deren verwendung zur weiterverarbeitung
DE3322894A1 (de) * 1983-06-23 1985-01-03 Schering AG, 1000 Berlin und 4709 Bergkamen Neue (beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel (h)

Also Published As

Publication number Publication date
HU200457B (en) 1990-06-28
AU3357084A (en) 1985-04-04
US4623649A (en) 1986-11-18
AU578043B2 (en) 1988-10-13
IE57670B1 (en) 1993-02-24
PT79264A (de) 1984-10-01
HUT35673A (en) 1985-07-29
ATE55604T1 (de) 1990-09-15
EP0137390A1 (de) 1985-04-17
FI843777A0 (fi) 1984-09-26
DE3335323A1 (de) 1985-04-04
ZA847619B (en) 1985-05-29
CA1263394A (en) 1989-11-28
ES536199A0 (es) 1985-06-01
IE842447L (en) 1985-03-27
GR80482B (en) 1985-01-28
DK456484D0 (da) 1984-09-25
DK170256B1 (da) 1995-07-17
NO843861L (no) 1985-03-28
IL73071A0 (en) 1984-12-31
NO160998C (no) 1989-06-21
FI843777A7 (fi) 1985-03-28
DD223714A5 (de) 1985-06-19
FI843777L (fi) 1985-03-28
DE3482984D1 (de) 1990-09-20
PT79264B (de) 1986-08-08
EP0137390B1 (de) 1990-08-16
JPS60100577A (ja) 1985-06-04
NO160998B (no) 1989-03-13
IL73071A (en) 1988-06-30
ES8505368A1 (es) 1985-06-01
DK456484A (da) 1985-03-28

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